Article
Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses.
European archives of psychiatry and clinical neuroscience - 1 Dec 2022
Kalman Janos L, Yoshida Tomoya, Andlauer Till F M, Schulte Eva C, Adorjan Kristina, Alda Martin, Ardau Raffaela, Aubry Jean-Michel, Brosch Katharina, Budde Monika, Chillotti Caterina, Czerski Piotr M, DePaulo Raymond J, Forstner Andreas, Goes Fernando S, Grigoroiu-Serbanescu Maria, Grof Paul, Grotegerd Dominik, Hahn Tim, Heilbronner Maria, Hasler Roland, Heilbronner Urs, Heilmann-Heimbach Stefanie, Kapelski Pawel, Kato Tadafumi, Kohshour Mojtaba Oraki, Meinert Susanne, Meller Tina, Nenadić Igor, Nöthen Markus M, Novak Tomas, Opel Nils, Pawlak Joanna, Pfarr Julia-Katharina, Potash James B, Reich-Erkelenz Daniela, Repple Jonathan, Richard-Lepouriel Hélène, Rietschel Marcella, Ringwald Kai G, Rouleau Guy, Schaupp Sabrina, Senner Fanny, Severino Giovanni, Squassina Alessio, Stein Frederike, Stopkova Pavla, Streit Fabian, Thiel Katharina, Thomas-Odenthal Florian, Turecki Gustavo, Twarowska-Hauser Joanna, Winter Alexandra, Zandi Peter P, Kelsoe John R, Falkai Peter, Dannlowski Udo, Kircher Tilo, Schulze Thomas G, Papiol Sergi
Abstract excerpt
Personality traits influence risk for suicidal behavior. We examined phenotype- and genotype-level associations between the Big Five personality traits and suicidal ideation and attempt in major depressive, bipolar and schizoaffective disorder, and schizophrenia patients (N = 3012) using fixed- and random-effects inverse variance-weighted meta-analyses. Suicidal ideations were more likely to be reported by...
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