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Developmental alterations in DNA methylation during gametogenesis from primordial germ cells to sperm

19 Jan 2022

Abstract excerpt

Because epigenetics is a critical component for gene expression, the hypothesis was tested that DNA methylation alterations are dynamic and continually change throughout gametogenesis to generate the mature sperm. Developmental alterations and stage-specific DNA methylation during gametogenesis from primordial germ cells (PGCs) to mature sperm are investigated. Individual developmental stage germ cells were...

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PMID: 35146397
DOI: 10.1016/j.isci.2022.103786

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