Two-Sample Mendelian Randomization Analysis Investigates Causal Associations Between Gut Microbial Genera and Inflammatory Bowel Disease, and Specificity Causal Associations in Ulcerative Colitis or Crohn’s Disease

Abstract excerpt

Background Intestinal dysbiosis is associated with inflammatory bowel disease (IBD). Ulcerative colitis (UC) and Crohn’s disease (CD), two subtypes of IBD, are characterized by unique microbial signatures, respectively. However, it is unclear whether UC or CD has a specific causal relationship with gut microbiota. Objective To investigate the potential causal associations between gut microbial genera and IBD, UC,...

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• Clostridium difficile and Clostridium perfringens research
• Gut microbiota and health
• Inflammatory Bowel Disease