Article
Genome-edited powdery mildew resistance in wheat without growth penalties.
Nature - 1 Feb 2022
Li Shengnan, Lin Dexing, Zhang Yunwei, Deng Min, Chen Yongxing, Lv Bin, Li Boshu, Lei Yuan, Wang Yanpeng, Zhao Long, Liang Yueting, Liu Jinxing, Chen Kunling, Liu Zhiyong, Xiao Jun, Qiu Jin-Long, Gao Caixia
Abstract excerpt
Disruption of susceptibility (S) genes in crops is an attractive breeding strategy for conferring disease resistance1,2. However, S genes are implicated in many essential biological functions and deletion of these genes typically results in undesired pleiotropic effects1. Loss-of-function mutations in one such S gene, Mildew resistance locus O (MLO), confers durable and broad-spectrum resistance to powdery mildew...
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