Article
[Associations between TGF-β1 G/A and TNF-α 308 G/A gene polymorphisms with airway resistance in chronic obstructive pulmonary disease].
Tuberkuloz ve toraks - 1 Jan 2013
Melek Kevser, Ulubay Gaye, Sarınç Ulaşlı Sevinç, Verdi Hasibe, Ataç Belgin, Öner Eyüboğlu Füsun
Abstract excerpt
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is an important morbidity and mortality cause all over the world. Although specific gene region has not been defined in the pathogenesis of COPD, cytokine gene polymorphisms like tumor necrosis factor-alfa (TNF-α) and transforming growth factor-beta1 (TGF-β1) may contribute to the development of COPD. The aim of the present study was to evaluate the...
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