The effects of epistasis and linkage on the invasion of locally beneficial mutations and the evolution of genomic islands.

Abstract excerpt

We study local adaptation of a peripheral population by investigating the fate of new mutations using a haploid two-locus two-allele continent-island migration model. We explore how linkage, epistasis, and maladaptive gene flow affect the invasion probability of weakly beneficial de-novo mutations that arise on the island at an arbitrary physical distance to a locus that already maintains a stable...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epistasis, Genetic
• Share to Genomic Islands
• Share to Models, Genetic