Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma

1 Feb 2022

Abstract excerpt

Epstein-Barr virus (EBV) was the first oncogenic virus identified in humans. It is primarily associated with multiple lymphoid and epithelial cancers, including nasopharyngeal carcinoma (NPC). However, its association with ferroptosis and its role in cancer therapy resistance have not been fully elucidated. Here, we show that EBV infection reduces the sensitivity of NPC cells to ferroptosis by activating the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35105963
DOI: 10.1038/s41418-022-00939-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinomaPMID 35105963Read ↗

PRMT4 Reduced Erastin-Induced Ferroptosis in Nasopharyngeal Carcinoma Cisplatin-Resistant Cells by Nrf2/GPX4 PathwaySemantic proximity Read ↗

Ferroptosis-related gene ATG5 is a novel prognostic biomarker in nasopharyngeal carcinoma and head and neck squamous cell carcinomaSemantic proximity Read ↗

RRFERV stabilizes TEAD1 expression to mediate nasopharyngeal cancer radiation resistance rendering tumor cells vulnerable to ferroptosisSemantic proximity Read ↗

TMEM160 inhibits KEAP1 to suppress ferroptosis and induce chemoresistance in gastric cancerSemantic proximity Read ↗

GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4Semantic proximity Read ↗

Changes in the Nasopharyngeal Carcinoma Nuclear Proteome Induced by the EBNA1 Protein of Epstein-Barr Virus Reveal Potential Roles for EBNA1 in Metastasis and Oxidative Stress ResponsesSemantic proximity Read ↗

Pan-Cancer Analysis of the Role of the Ferroptosis-Related Biomarker GPX4: A Potential Target for Prognosis and ImmunotherapySemantic proximity Read ↗

Exploration of the Critical Roles and Molecular Mechanisms of KIF2C and GPX4 Genes in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Ferroptosis and Nrf2 Signaling in Head and Neck Cancer: Resistance Mechanisms and Therapeutic ProspectsSemantic proximity Read ↗

PKCiota Inhibits the Ferroptosis of Esophageal Cancer Cells via Suppressing USP14-Mediated Autophagic Degradation of GPX4Semantic proximity Read ↗

TP53 Mediated Transcriptional Regulation of PHKG2 Promotes Ferroptosis in Head and Neck Squamous Cell Carcinoma by Inhibiting the NRF2/GPX4 PathwaySemantic proximity Read ↗

BHRF1 Enhances EBV Mediated Nasopharyngeal Carcinoma Tumorigenesis through Modulating Mitophagy Associated with Mitochondrial Membrane Permeabilization TransitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.