Article
Survival in branching cellular populations.
Theoretical population biology - 1 Apr 2022
Bryant Adam S, Lavrentovich Maxim O
Abstract excerpt
We analyze evolutionary dynamics in a confluent, branching cellular population, such as in a growing duct, vasculature, or in a branching microbial colony. We focus on the coarse-grained features of the evolution and build a statistical model that captures the essential features of the dynamics. Using simulations and analytic approaches, we show that the survival probability of strains within the growing...
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