Article
Genetic diversity in L1 ORF of human papillomavirus in women with cervical cancer with and without human immunodeficiency virus in Botswana and Kenya.
BMC infectious diseases - 27 Jan 2022
Tawe Leabaneng, Choga Wonderful T, Paganotti Giacomo M, Bareng Ontlametse T, Ntereke Tlhalefo D, Ramatlho Pleasure, Ditshwanelo Doreen, Gaseitsiwe Simani, Kasvosve Ishmael, Ramogola-Masire Doreen, Orang'o Omenge E, Robertson Erle, Zetola Nicola, Moyo Sikhulile, Grover Surbhi, Ermel Aaron C
Abstract excerpt
BACKGROUND: The variation of human papillomavirus (HPV) genotypes shapes the risks of cervical cancer and these variations are not well defined in Africa. Nucleotide changes within the L1 gene, nucleotide variability, and phylogeny were explored in relation to HIV in samples from Botswana and Kenya. METHODS: A total of 98 HPV-positive cervical samples were sequenced to identify different HPV variants....
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