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Large-scale characterization of the macrolide resistome reveals high diversity and several new pathogen-associated genes

17 Jan 2022

Abstract excerpt

Macrolides are broad-spectrum antibiotics used to treat a range of infections. Resistance to macrolides is often conferred by mobile resistance genes encoding Erm methyltransferases or Mph phosphotransferases. New erm and mph genes keep being discovered in clinical settings but their origins remain unknown, as is the type of macrolide resistance genes that will appear in the future. In this study, we used...

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PMID: 35084301
DOI: 10.1099/mgen.0.000770

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