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Differential Orthopedia Homeobox expression in pulmonary carcinoids is associated with changes in DNA methylation

25 Jan 2022

Abstract excerpt

Abstract Limited number of tumor types have been examined for Orthopedia Homeobox (OTP) expression. In pulmonary carcinoids, loss of expression is a strong indicator of poor prognosis. Here, we investigated OTP expression in 37 different tumor types, and the association between OTP expression and DNA methylation levels in lung neuroendocrine neoplasms. We analyzed publicly available multi‐omics data...

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PMID: 35076935
DOI: 10.1002/ijc.33939

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