Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipoprotein subfractions highly associated with renal damage in familial lecithin:cholesterol acyltransferase deficiency.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2014

Kuroda Masayuki, Holleboom Adriaan G, Stroes Erik S G, Asada Sakiyo, Aoyagi Yasuyuki, Kamata Kouju, Yamashita Shizuya, Ishibashi Shun, Saito Yasushi, Bujo Hideaki

Abstract excerpt

OBJECTIVE: In familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD), deposition of abnormal lipoproteins in the renal stroma ultimately leads to renal failure. However, fish-eye disease (FED) does not lead to renal damage although the causative mutations for both FLD and FED lie within the same LCAT gene. This study was performed to identify the lipoproteins important for the development of renal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, Gel
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme Replacement Therapy

Share to Kidney

Share to Lipoproteins

Share to Phosphatidylcholine-Sterol O-Acyltransferase

Share to Proteinuria

Share to Renal Insufficiency

Source

Identifiers

PMID: 24876348
DOI: 10.1161/ATVBAHA.114.303420

Genes

LCAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipoprotein subfractions highly associated with renal damage in familial lecithin:cholesterol acyltransferase deficiency.PMID 24876348Read ↗

Novel therapeutic opportunities for familial lecithin:cholesterol acyltransferase deficiency: promises and challenges.Semantic proximity Read ↗

A systematic review of the natural history and biomarkers of primary lecithin:cholesterol acyltransferase deficiency.Semantic proximity Read ↗

The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families.Semantic proximity Read ↗

The molecular pathology of lecithin:cholesterol acyltransferase (LCAT) deficiency syndromes.Semantic proximity Read ↗

Possible induction of renal dysfunction in patients with lecithin:cholesterol acyltransferase deficiency by oxidized phosphatidylcholine in glomeruli.Semantic proximity Read ↗

Lecithin: cholesterol acyltransferase deficiency and fish-eye diseaseSemantic proximity Read ↗

T13M mutation of lecithin-cholesterol acyltransferase gene causes fish-eye disease.Semantic proximity Read ↗

[Familial LCAT deficiency].Semantic proximity Read ↗

Compound heterozygosity (G71R/R140H) in the lecithin:cholesterol acyltransferase (LCAT) gene results in an intermediate phenotype between LCAT-deficiency and fish-eye disease.Semantic proximity Read ↗

[Lecithin: cholesterol acyltransferase (LCAT)--the genetic analysis of familial LCAT deficiency and fish eye disease].Semantic proximity Read ↗

Characterization of a new LCAT mutation causing familial LCAT deficiency (FLD) and the role of APOE as a modifier gene of the FLD phenotype.Semantic proximity Read ↗

Complete and Partial Lecithin:Cholesterol Acyltransferase Deficiency Is Differentially Associated With Atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.