Article
Phenotypic and Genomic Comparison of Klebsiella pneumoniae Lytic Phages: vB_KpnM-VAC66 and vB_KpnM-VAC13.
Viruses - 21 Dec 2021
Pacios Olga, Fernández-García Laura, Bleriot Inés, Blasco Lucia, Ambroa Antón, López María, Ortiz-Cartagena Concha, Cuenca Felipe Fernández, Oteo-Iglesias Jesús, Pascual Álvaro, Martínez-Martínez Luis, Domingo-Calap Pilar, Tomás María
Abstract excerpt
Klebsiella pneumoniae is a human pathogen that worsens the prognosis of many immunocompromised patients. Here, we annotated and compared the genomes of two lytic phages that infect clinical strains of K. pneumoniae (vB_KpnM-VAC13 and vB_KpnM-VAC66) and phenotypically characterized vB_KpnM-VAC66 (time of adsorption of 12 min, burst size of 31.49 ± 0.61 PFU/infected cell, and a host range of 20.8% of the tested...
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