Article
Development of Epigenetic Clocks for Key Ruminant Species.
Genes - 30 Dec 2021
Caulton Alex, Dodds Ken G, McRae Kathryn M, Couldrey Christine, Horvath Steve, Clarke Shannon M
Abstract excerpt
Robust biomarkers of chronological age have been developed in humans and model mammalian species such as rats and mice using DNA methylation data. The concept of these so-called "epigenetic clocks" has emerged from a large body of literature describing the relationship between genome-wide methylation levels and age. Epigenetic clocks exploit this phenomenon and use small panels of differentially methylated...
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