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Article

Patritumab Deruxtecan: Paving the Way for EGFR-TKI–Resistant NSCLC

1 Jan 2022

Abstract excerpt

Abstract Summary: HER3 is ubiquitously expressed in EGFR-mutant non–small cell lung cancer (NSCLC) irrespective of resistant mechanisms to EGFR tyrosine kinase inhibitors, thus garnering attention as a valuable therapeutic target. In this issue of Cancer Discovery, Jänne and colleagues highlight early clinical data supporting patritumab deruxtecan as a potentially appreciable agent for previously treated...

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PMID: 35022206
DOI: 10.1158/2159-8290.cd-21-1429

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