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Article

Predictive value of TCR Vβ-Jβ profile for adjuvant gefitinib in EGFR mutant NSCLC from ADJUVANT-CTONG 1104 trial.

JCI insight - 11 Jan 2022

Chen Cunte, Liu Si-Yang Maggie, Chen Yedan, Ou Qiuxiang, Bao Hua, Xu Ling, Zhang Yikai, Zhong Wenzhao, Zhou Qing, Yang Xue-Ning, Shao Yang, Wu Yi-Long, Liu Si-Yang, Li Yangqiu

Abstract excerpt

Herein, we characterize the landscape and prognostic significance of the T cell receptor (TCR) repertoire of early-stage non-small cell lung cancer (NSCLC) for patients with an epidermal growth factor receptor (EGFR) mutation. β Chain TCR sequencing was used to characterize the TCR repertoires of paraffin-preserved pretreatment tumor and tumor-adjacent tissues from 57 and 44 patients with stage II/III NSCLC with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35014626
DOI: 10.1172/jci.insight.152631
PMCID: PMC8765044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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