Article
An ancient positively selected BMPRIB missense variant increases litter size of Mongolian sheep populations following latitudinal gradient.
Molecular genetics and genomics : MGG - 1 Jan 2022
Chong Yuqing, Jiang Xunping, Liu Guiqiong
Abstract excerpt
New gene mutation origination is a driving force for the evolution of organisms. The effect of FecB mutation in BMPRIB gene on the litter size of sheep has been well known for a long time, each copy of the mutant allele increases litter size by 0.4-0.5. However, the origin and adaptive evolution mechanism of FecB mutation are still unclear. Here we carried on the thorough analysis on evolutionary features of...
Topics
- Animals
- Bone Morphogenetic Protein Receptors, Type I
- China
- Female
- Genetic Speciation
- Genotype
- Litter Size
- Mongolia
- Mutation, Missense
- Phylogeny
- Phylogeography
- Polymorphism, Single Nucleotide
- Pregnancy
- Pregnancy, Animal
- Selection, Genetic
- Sheep