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Article

Synthesis of Dolichols in Candida albicans Is Co-Regulated with Elongation of Fatty Acids.

International journal of molecular sciences - 30 Dec 2021

Janik Anna, Perlińska-Lenart Urszula, Gawarecka Katarzyna, Augustyniak Justyna, Bratek-Gerej Ewelina, Bernat Przemysław, Piłsyk Sebastian, Skalmowska Patrycja, Palamarczyk Grażyna, Swiezewska Ewa, Kruszewska Joanna S

Abstract excerpt

Protein glycosylation requires dolichyl phosphate as a carbohydrate carrier. Dolichols are α-saturated polyprenols, and their saturation in S. cerevisiae is catalyzed by polyprenyl reductase Dfg10 together with some other unknown enzymes. The aim of this study was to identify such enzymes in Candida. The Dfg10 polyprenyl reductase from S. cerevisiae comprises a C-terminal 3-oxo-5-alpha-steroid 4-dehydrogenase...

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Share to Acetyl Coenzyme A
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35008833
DOI: 10.3390/ijms23010409
PMCID: PMC8745096

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