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Article

Weight-gain propensity and morphine withdrawal alters locomotor behavior and regional norepinephrine-related gene expression in male and female mice.

Pharmacology, biochemistry, and behavior - 1 Feb 2022

Li Xinyi, Kshatriya Dushyant, Bello Nicholas T

Abstract excerpt

Interactions between obesity and opioid use are poorly understood. The objective of this study was to determine whether phenotypic differences in diet-induced weight gain altered morphine withdrawal responses. Male and female C57BL/6J mice were characterized as obese prone (OP) or obese resistant (OR) based on median split in body weights following exposure to high-fat diet (45% fat). After classification into OP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35007656
DOI: 10.1016/j.pbb.2022.173329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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