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Article

Cross-species considerations in models of neurodevelopmental disorders.

Trends in neurosciences - 1 Mar 2022

Till Sally M, Hickson Raven D L, Kind Peter C

Abstract excerpt

Advances in genetic technologies have facilitated the development of new animal models of neurodevelopmental disorders (NDDs), enabling cross-species validation of disease-related phenotypes and exploration of species-specific behaviours. In a recent study, Berg et al. used a rat model of Angelman Syndrome (AS) to identify Ube3a-dependent social behaviours, highlighting potential cross-species convergence and...

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PMID: 34998618
DOI: 10.1016/j.tins.2021.12.005

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