Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Six generations of CHMP2B-mediated Frontotemporal Dementia: Clinical features, predictive testing, progression, and survival.

Acta neurologica Scandinavica - 1 May 2022

Roos Peter, Johannsen Peter, Lindquist Suzanne G, Brown Jeremy M, Waldemar Gunhild, Duno Morten, Nielsen Troels T, Budtz-Jørgensen Esben, Gydesen Susanne, Holm Ida E, Collinge John, Isaacs Adrian M, Nielsen Jørgen E

Abstract excerpt

OBJECTIVES: Chromosome 3-linked frontotemporal dementia (FTD-3) is caused by a c.532-1G > C mutation in the CHMP2B gene. It is extensively studied in a Danish family comprising one of the largest families with an autosomal dominantly inherited frontotemporal dementia (FTD). This retrospective cohort study utilizes demographics to identify risk factors for onset, progression, life expectancy, and death in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frontotemporal Dementia

Share to Mutation

Share to Nerve Tissue Proteins

Source

Identifiers

PMID: 34997757
DOI: 10.1111/ane.13578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Six generations of CHMP2B-mediated Frontotemporal Dementia: Clinical features, predictive testing, progression, and survival.PMID 34997757Read ↗

Frontotemporal dementia linked to chromosome 3 (FTD-3)--current concepts and the detection of a previously unknown branch of the Danish FTD-3 family.Semantic proximity Read ↗

Cognitive impairment in the preclinical stage of dementia in FTD-3 CHMP2B mutation carriers: a longitudinal prospective study.Semantic proximity Read ↗

Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study.Semantic proximity Read ↗

TMEM106B and ApoE polymorphisms in CHMP2B-mediated frontotemporal dementia (FTD-3).Semantic proximity Read ↗

Frontotemporal dementia caused by CHMP2B mutations.Semantic proximity Read ↗

Genetic variability in CHMP2B and frontotemporal dementia.Semantic proximity Read ↗

CHMP2B mutations are not a cause of dementia in Dutch patients with familial and sporadic frontotemporal dementia.Semantic proximity Read ↗

Genetic background predicts poor prognosis in frontotemporal lobar degeneration.Semantic proximity Read ↗

Development and validation of pedigree classification criteria for frontotemporal lobar degeneration.Semantic proximity Read ↗

Personalised penetrance estimation for C9orf72-related amyotrophic lateral sclerosis and frontotemporal dementiaSemantic proximity Read ↗

Mendelian forms of disease and age at onset affect survival in frontotemporal dementia.Semantic proximity Read ↗

The Heritability of Frontotemporal Lobar Degeneration: Validation of Pedigree Classification Criteria in a Northern Italy Cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.