Article
[Changes in the antigenic phenotype of mouse thymocytes after exposure to chemical inducers of differentiation and ionizing radiation].
Radiobiologiia - 1 Jan 2000
Sorokina N I, Miroshnichenko I V, Nikonova M F, Aknazarova R Kh, Mikhna M G
Abstract excerpt
Irradiation of a mouse thymocyte fraction enriched by T-lymphocyte precursors changes the antigenic phenotype of cells toward the increase of their highly differentiated forms. Similar changes in membrane marker antigens are produced by chemical inductors of differentiation and thymotropin. The changes in the cell phenotype induced by the above agents are associated with both membrane and intragenome...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Cell Differentiation
- Cytotoxicity Tests, Immunologic
- DNA Damage
- H-2 Antigens
- Mice
- Mice, Inbred CBA
- Phenotype
- Puromycin
- T-Lymphocytes
