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Article

Genomic, Immunological, and Clinical Characterization of Pyroptosis in Ovarian Cancer

1 Dec 2021

Abstract excerpt

PURPOSE: Pyroptosis is a form of lytic programmed cell death that is associated with the pathogenesis of many tumors. However, the potential roles of pyroptosis-related genes (PRGs) in the tumor microenvironment (TME) remain unclear. MATERIALS AND METHODS: We systematically described the genetic and transcriptional alterations in PRGs in gynecological cancers. An unsupervised clustering method was used to...

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PMID: 34992421
DOI: 10.2147/jir.s344554

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