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Article

Divergent time-varying connectivity of thalamic sub-regions characterizes clinical phenotypes and cognitive status in multiple sclerosis.

Molecular psychiatry - 1 Mar 2022

Carotenuto Antonio, Valsasina Paola, Hidalgo de la Cruz Milagros, Cacciaguerra Laura, Preziosa Paolo, Marchesi Olga, Filippi Massimo, Rocca Maria A

Abstract excerpt

We aimed to investigate abnormal time-varying functional connectivity (FC) for thalamic sub-regions in multiple sclerosis (MS) and their clinical, cognitive and MRI correlates. Eighty-nine MS patients (49 relapsing-remitting [RR] MS; 40 progressive [P] MS) and 53 matched healthy controls underwent neurological, neuropsychological and resting state fMRI assessment. Time-varying connectivity (TVC) was quantified...

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Identifiers

PMID: 34992237
DOI: 10.1038/s41380-021-01401-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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