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Article

Novel EWSR1-SMAD3 Gene Fusions in a Group of Acral Fibroblastic Spindle Cell Neoplasms.

The American journal of surgical pathology - 1 Apr 2018

Kao Yu-Chien, Flucke Uta, Eijkelenboom Astrid, Zhang Lei, Sung Yun-Shao, Suurmeijer Albert J H, Antonescu Cristina R

Abstract excerpt

Benign/low-grade fibroblastic tumors encompass a broad spectrum of tumors with different morphologies and molecular genetic abnormalities. However, despite significant progress in recent genomic characterization, there are still tumors in this histologic spectrum that are difficult to classify, lacking known molecular characteristics. Triggered by a challenging congenital spindle cell neoplasm arising in the heel...

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Topics

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Share to Fibroblasts
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

Share to RNA-Binding Protein EWS

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Share to Transcriptional Regulator ERG

Source

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Identifiers

PMID: 29309308
DOI: 10.1097/PAS.0000000000001002
PMCID: PMC5844807

Genes

EWSR1
SMAD3
ERG

Provenance

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