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Clinicopathological and genetic study of a rare occurrence: Malignant transformation of fibrous dysplasia of the jaws

1 Jan 2022

Abstract excerpt

BACKGROUND: Malignant transformation of fibrous dysplasia (FD) is very rare and little is known about this occurrence. METHODS: We present the detailed clinical course of three cases of osteosarcoma arising from FD of the jaws and explore the genetic aberrations by Sanger sequencing, whole-exome sequencing (WES) and immunohistochemistry (IHC). A literature review of important topics related to this occurrence was...

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PMID: 34989160
DOI: 10.1002/mgg3.1861

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