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Article

Ovarian Aging: Role of Pituitary-Ovarian Axis Hormones and ncRNAs in Regulating Ovarian Mitochondrial Activity.

Frontiers in endocrinology - 1 Jan 2021

Colella Marco, Cuomo Danila, Peluso Teresa, Falanga Ilaria, Mallardo Massimo, De Felice Mario, Ambrosino Concetta

Abstract excerpt

The number of mitochondria in the oocyte along with their functions (e.g., energy production, scavenger activity) decline with age progression. Such multifaceted functions support several processes during oocyte maturation, ranging from energy supply to synthesis of the steroid hormones. Hence, it is hardly surprising that their impairment has been reported in both physiological and premature ovarian aging,...

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Identifiers

PMID: 34975760
DOI: 10.3389/fendo.2021.791071
PMCID: PMC8716494

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