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Epigenetic Age Acceleration Is Not Associated with Age-Related Macular Degeneration

15 Dec 2021

Abstract excerpt

DNA methylation age (DNAm age) estimation is a powerful biomarker of human ageing. To date, epigenetic clocks have not been evaluated in age-related macular degeneration (AMD). Here, we perform genome-wide DNA methylation analyses in blood of AMD patients with a documented smoking history (14 AMD, 16 Normal), identifying loci of differential methylation (DML) with a relaxed p-value criterion (p ≤ 10−4). We...

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PMID: 34948253
DOI: 10.3390/ijms222413457

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