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Article

LTBP3 Frameshift Variant in British Shorthair Cats with Complex Skeletal Dysplasia.

Genes - 29 Nov 2021

Rudd Garces Gabriela, Knebel Anna, Hülskötter Kirsten, Jagannathan Vidhya, Störk Theresa, Hewicker-Trautwein Marion, Leeb Tosso, Volk Holger A

Abstract excerpt

We investigated a highly inbred family of British Shorthair cats in which two offspring were affected by deteriorating paraparesis due to complex skeletal malformations. Radiographs of both affected kittens revealed vertebral deformations with marked stenosis of the vertebral canal from T11 to L3. Additionally, compression of the spinal cord, cerebellar herniation, coprostasis and hypogangliosis were found. The...

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Identifiers

PMID: 34946872
DOI: 10.3390/genes12121923
PMCID: PMC8701722

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