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The Nuts and Bolts of SARS-CoV-2 Spike Receptor-Binding Domain Heterologous Expression

2 Dec 2021

Abstract excerpt

COVID-19 is a highly infectious disease caused by a newly emerged coronavirus (SARS-CoV-2) that has rapidly progressed into a pandemic. This unprecedent emergency has stressed the significance of developing effective therapeutics to fight the current and future outbreaks. The receptor-binding domain (RBD) of the SARS-CoV-2 surface Spike protein is the main target for vaccines and represents a helpful “tool” to...

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PMID: 34944456
DOI: 10.3390/biom11121812

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