Article
Evidence of the Involvement of a Cyclase Gene in the Biosynthesis of Ochratoxin A in Aspergillus carbonarius.
Toxins - 13 Dec 2021
Ferrara Massimo, Gallo Antonia, Cervini Carla, Gambacorta Lucia, Solfrizzo Michele, Baker Scott E, Perrone Giancarlo
Abstract excerpt
Ochratoxin A (OTA) is a well-known mycotoxin with wide distribution in food and feed. Fungal genome sequencing has great utility for identifying secondary metabolites gene clusters for known and novel compounds. A comparative analysis of the OTA-biosynthetic cluster in A. steynii, A. westerdijkiae, A. niger, A. carbonarius, and P. nordicum has revealed a high synteny in OTA cluster organization in five structural...
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