Article
Functional roles of LaeA, polyketide synthase, and glucose oxidase in the regulation of ochratoxin A biosynthesis and virulence in Aspergillus carbonarius.
Molecular plant pathology - 1 Jan 2021
Maor Uriel, Barda Omer, Sadhasivam Sudharsan, Bi Yang, Levin Elena, Zakin Varda, Prusky Dov B, Sionov Edward
Abstract excerpt
Aspergillus carbonarius is the major producer of ochratoxin A (OTA) among Aspergillus species, but the contribution of this secondary metabolite to fungal virulence has not been assessed. We characterized the functions and addressed the roles of three factors in the regulation of OTA synthesis and pathogenicity in A. carbonarius: LaeA, a transcriptional factor regulating the production of secondary metabolites;...
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