Article
Genome placement of alpha-haemolysin cluster is associated with alpha-haemolysin sequence variation, adhesin and iron acquisition factor profile of Escherichia coli.
Microbial genomics - 1 Dec 2021
Kolenda Rafał, Sidorczuk Katarzyna, Noszka Mateusz, Aleksandrowicz Adrianna, Khan Muhammad Moman, Burdukiewicz Michał, Pickard Derek, Schierack Peter
Abstract excerpt
Since the discovery of haemolysis, many studies focused on a deeper understanding of this phenotype in Escherichia coli and its association with other virulence genes, diseases and pathogenic attributes/functions in the host. Our virulence-associated factor profiling and genome-wide association analysis of genomes of haemolytic and nonhaemolytic E. coli unveiled high prevalence of adhesins, iron acquisition genes...
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