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Article

Omicron N501Y mutation among SARS-CoV-2 lineages: Insilico analysis of potent binding to tyrosine kinase and hypothetical repurposed medicine.

Travel medicine and infectious disease - 1 Jan 2000

Kazybay Bexultan, Ahmad Ashfaq, Mu Chenglin, Mengdesh Diana, Xie Yingqiu

Abstract excerpt

Variants of SARS-CoV-2 lineages including the most recently circulated Omicron, and previous pandemic B.1.351, B.1.1.7, which have been public concerns, contain a N501Y mutation located in the spike receptor binding domain. However, the potential interactions with host cells linking N501Y mutation to pathogenic relevance remain elusive. Recently, we and others report that kinases such as PI3K/AKT signaling are...

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Identifiers

PMID: 34929375
DOI: 10.1016/j.tmaid.2021.102242
PMCID: PMC8677628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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