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Article

Identification of Pharmacological Autophagy Regulators of Active Ulcerative Colitis

1 Dec 2021

Abstract excerpt

Background: Ulcerative colitis (UC) is a chronic recurrent disease of unknown etiology. Recently, it has been reported that autophagy-related gene polymorphism is closely associated with increased risk of UC, and the therapeutic effect of some UC drugs is mediated by regulating autophagy pathways. This study aims to identify pivotal autophagy-related regulators in UC pathogenesis and provide novel molecular...

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PMID: 34925026
DOI: 10.3389/fphar.2021.769718

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