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Testing for Inherited Susceptibility to Breast Cancer.

Hematology/oncology clinics of North America - 1 Feb 2023

Robson Mark

Abstract excerpt

When BRCA1 and BRCA2 were first identified, the initial models for delivering testing were shaped by concepts of genetic exceptionalism and a lack of data regarding therapeutic implications and the effectiveness of risk reduction. Since then, interventions have been effective, and treatment implications have become clear. The sensitivity of guideline-based testing is incomplete, leading to calls for universal...

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PMID: 36435609
DOI: 10.1016/j.hoc.2022.08.003

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