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Pan-cancer single-cell landscape of tumor-infiltrating T cells

16 Dec 2021

Abstract excerpt

An atlas of cancer-associated T cells The tumor microenvironment contains many different kinds of immune cells, the composition, function, and roles of which are unclear. Using single-cell RNA sequencing of T cells in 21 cancer types from more than 300 patients, Zheng et al . identified differences in transcript composition that could be used to catalog different T cell types (see the Perspective by van der Leun...

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PMID: 34914499
DOI: 10.1126/science.abe6474

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