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Article

Selenium and cancer risk: Wide-angled Mendelian randomization analysis.

International journal of cancer - 1 Apr 2022

Yuan Shuai, Mason Amy M, Carter Paul, Vithayathil Mathew, Kar Siddhartha, Burgess Stephen, Larsson Susanna C

Abstract excerpt

Evidence on the association between selenium and cancer risk is inconclusive. We conducted a Mendelian randomization study to examine the associations of selenium levels with 22 site-specific cancers and any cancer. Single nucleotide polymorphisms (SNPs) strongly associated with toenail and blood (TAB) and blood selenium levels in mild linkage disequilibrium (r2 < .3) were used as instrumental variables. Genetic...

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Identifiers

PMID: 34910310
DOI: 10.1002/ijc.33902
PMCID: PMC7613914

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