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Article

Forward and reverse genetic dissection of morphogenesis identifies filament-competent Candida auris strains.

Nature communications - 10 Dec 2021

Santana Darian J, O'Meara Teresa R

Abstract excerpt

Candida auris is an emerging healthcare-associated pathogen of global concern. Recent reports have identified C. auris isolates that grow in cellular aggregates or filaments, often without a clear genetic explanation. To investigate the regulation of C. auris morphogenesis, we applied an Agrobacterium-mediated transformation system to all four C. auris clades. We identified aggregating mutants associated with...

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Identifiers

PMID: 34893621
DOI: 10.1038/s41467-021-27545-5
PMCID: PMC8664941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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