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Clinical isolates of Candida auris with enhanced adherence and biofilm formation due to genomic amplification of ALS4

13 Mar 2023

Abstract excerpt

Candida auris is an emerging multidrug-resistant fungal pathogen and a new global threat to human health. A unique morphological feature of this fungus is its multicellular aggregating phenotype, which has been thought to be associated with defects in cell division. In this study, we report a new aggregating form of two clinical C. auris isolates with increased biofilm forming capacity due to enhanced adherence...

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PMID: 36913408
DOI: 10.1371/journal.ppat.1011239

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