Article
Fine-scale population structure and demographic history of British Pakistanis.
Nature communications - 10 Dec 2021
Arciero Elena, Dogra Sufyan A, Malawsky Daniel S, Mezzavilla Massimo, Tsismentzoglou Theofanis, Huang Qin Qin, Hunt Karen A, Mason Dan, Sharif Saghira Malik, van Heel David A, Sheridan Eamonn, Wright John, Small Neil, Carmi Shai, Iles Mark M, Martin Hilary C
Abstract excerpt
Previous genetic and public health research in the Pakistani population has focused on the role of consanguinity in increasing recessive disease risk, but little is known about its recent population history or the effects of endogamy. Here, we investigate fine-scale population structure, history and consanguinity patterns using genotype chip data from 2,200 British Pakistanis. We reveal strong recent population...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.