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[Different Subtypes Caused by c.721C>T Substitution in the Exon 7 of ABO Gene].

Zhongguo shi yan xue ye xue za zhi - 1 Dec 2021

Xiao Jian-Yu, Feng Chen-Chen, Liu Tai-Xiang, Shi Li-Li, Zhang Ruo-Yang, Huang Cheng-Yin, Chen Qing

Abstract excerpt

OBJECTIVE: To analyze the different subtypes caused by c.721C>T substitution in the exon 7 of the ABO gene, and to investigate the related molecular mechanism of different antigens expression. METHODS: ABO subtypes in 7 samples were identified by standard serological methods. The exons 6, 7, and adjacent intron of ABO gene were amplified by Polymerase Chain Reaction (PCR), and the PCR products were analyzed by...

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PMID: 34893134
DOI: 10.19746/j.cnki.issn.1009-2137.2021.06.039

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