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Disturbances of the Gut Microbiota, Sleep Architecture, and mTOR Signaling Pathway in Patients with Severe Obstructive Sleep Apnea‐Associated Hypertension

1 Jan 2021

Abstract excerpt

Intermittent hypoxia and sleep fragmentation are pathophysiological processes involved in obstructive sleep apnea (OSA) which affect gut microbiota, sleep architecture, and mTOR signaling pathway. However, the involvement of these elements in the pathogenesis mechanism of OSA‐associated hypertension remains unclear. Therefore, this study investigated whether the OSA‐associated hypertension mechanism is regulated...

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PMID: 34888100
DOI: 10.1155/2021/9877053

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