Article
Genome-Wide Mutation Scoring for Machine-Learning-Based Antimicrobial Resistance Prediction.
International journal of molecular sciences - 2 Dec 2021
Májek Peter, Lüftinger Lukas, Beisken Stephan, Rattei Thomas, Materna Arne
Abstract excerpt
The prediction of antimicrobial resistance (AMR) based on genomic information can improve patient outcomes. Genetic mechanisms have been shown to explain AMR with accuracies in line with standard microbiology laboratory testing. To translate genetic mechanisms into phenotypic AMR, machine learning has been successfully applied. AMR machine learning models typically use nucleotide k-mer counts to represent genomic...
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