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Article

Flow cytometric analysis reveals culture condition dependent variations in phenotypic heterogeneity of Limosilactobacillus reuteri.

Scientific reports - 7 Dec 2021

Rao Nikhil Seshagiri, Lundberg Ludwig, Palmkron Shuai, Håkansson Sebastian, Bergenståhl Björn, Carlquist Magnus

Abstract excerpt

Optimisation of cultivation conditions in the industrial production of probiotics is crucial to reach a high-quality product with retained probiotic functionality. Flow cytometry-based descriptors of bacterial morphology may be used as markers to estimate physiological fitness during cultivation, and can be applied for online monitoring to avoid suboptimal growth. In the current study, the effects of temperature,...

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Identifiers

PMID: 34876641
DOI: 10.1038/s41598-021-02919-3
PMCID: PMC8651721

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