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Signature of long-lived memory CD8+ T cells in acute SARS-CoV-2 infection

7 Dec 2021

Abstract excerpt

Abstract Immunological memory is a hallmark of adaptive immunity and facilitates an accelerated and enhanced immune response upon re-infection with the same pathogen 1,2 . Since the outbreak of the ongoing COVID-19 pandemic, a key question has focused on which SARS-CoV-2-specific T cells stimulated during acute infection give rise to long-lived memory T cells 3 . Here, using spectral flow cytometry combined with...

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PMID: 34875673
DOI: 10.1038/s41586-021-04280-x

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