Article
A domestic cat whole exome sequencing resource for trait discovery.
Scientific reports - 30 Mar 2021
Rodney Alana R, Buckley Reuben M, Fulton Robert S, Fronick Catrina, Richmond Todd, Helps Christopher R, Pantke Peter, Trent Dianne J, Vernau Karen M, Munday John S, Lewin Andrew C, Middleton Rondo, Lyons Leslie A, Warren Wesley C
Abstract excerpt
Over 94 million domestic cats are susceptible to cancers and other common and rare diseases. Whole exome sequencing (WES) is a proven strategy to study these disease-causing variants. Presented is a 35.7 Mb exome capture design based on the annotated Felis_catus_9.0 genome assembly, covering 201,683 regions of the cat genome. Whole exome sequencing was conducted on 41 cats with known and unknown genetic diseases...
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