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Article

Association of genetic variants in PDGFRA with high myopia in the Han population of southwestern China.

Ophthalmic genetics - 1 Apr 2022

Jiang Lingxi, Huang Guo, Dai Chao, Zheng Rui, Xie Chunbao, Duan Suyang, Zhong Ling, Liu Xiaoqi, Gong Bo, Yao Dezhong, Yang Zhenglin, Shi Yi

Abstract excerpt

PURPOSE: To investigate the associations of 11 genetic single nucleotide polymorphisms (SNPs) in FRAP1 and PDGFRA with high myopia (HM) in a Han Chinese population. METHODS: A total of 442 HM patients and 947 healthy controls were recruited for this study. Five genetic models were analysed to further evaluate the association of target SNPs with HM. SNP functional annotation database tools were used to predict and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34865611
DOI: 10.1080/13816810.2021.1998550

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