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Article

Phenome risk classification enables phenotypic imputation and gene discovery in developmental stuttering.

American journal of human genetics - 2 Dec 2021

Shaw Douglas M, Polikowsky Hannah P, Pruett Dillon G, Chen Hung-Hsin, Petty Lauren E, Viljoen Kathryn Z, Beilby Janet M, Jones Robin M, Kraft Shelly Jo, Below Jennifer E

Abstract excerpt

Developmental stuttering is a speech disorder characterized by disruption in the forward movement of speech. This disruption includes part-word and single-syllable repetitions, prolongations, and involuntary tension that blocks syllables and words, and the disorder has a life-time prevalence of 6-12%. Within Vanderbilt's electronic health record (EHR)-linked biorepository (BioVU), only 142 individuals out of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34861174
DOI: 10.1016/j.ajhg.2021.11.004
PMCID: PMC8715184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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