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Proteomic Analysis gives Novel Insights into Candida Albicans Morphogenesis in the Wake of Ubiquitin Mutation UbEP42.

Cell biochemistry and biophysics - 1 Jun 2026

Dantuslia Sandeep Kumar, Prajapati Bhoomi, Prabha C Ratna

Abstract excerpt

Ubiquitin is pivotal to the regulation of protein homeostasis, signal transduction, and various cellular processes. Mutations in ubiquitin can disrupt many cellular functions. In this study LC-MS/MS proteomics approach was used to explore the effects of UbEP42, a dosage dependent lethal ubiquitin mutant, on the protein profile of Candida albicans. The biological processes and metabolic pathways associated with...

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PMID: 41806285
DOI: 10.1007/s12013-026-02041-z

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